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Home > Category > > Small Molecule Compound > BO-264

BO-264

Glpbio

Catalog No：GC39483-250mg CAS No.：2408648-20-2 MDLNo： Brand:Glpbio purity： 特性： Purpose:BO-264 是一種高效，口服活性的轉(zhuǎn)化酸性卷曲螺旋 3 (TACC3) 抑制劑，IC50 為 188 nM，Kd 為 1.5 nM。BO-264 特異性阻斷 FGFR3-TACC3 融合蛋白的功能。BO-264 誘導(dǎo)紡錘體檢查點依賴的有絲分裂阻滯，DNA 損傷和細胞凋亡 (apoptosis)。BO-264 具有廣譜抗腫瘤活性。DMSO: 50 mg/mL (141.49 mM)

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Product Overview

Product Name	BO-264
CAS	2408648-20-2
Formula	C₁₈H₁₉N₅O₃
MW	353.38
Storage condition	Store at -20°C

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BO-264

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